| | Travel (Km) | and then | to take | total (Km) | |
| | 0.0 | Start out at Galway,Galway | Uncl. | 0.0 | |
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| | 0.3 | At traffic signals turn left onto University Road (signposted City Centre) | Uncl. | 0.3 | |
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| | 0.5 | Cross Salmon Weir Bridge | Uncl. | 0.9 | |
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| | 0.1 | Turn right onto Saint Vincent's Avenue | Uncl. | 0.9 | |
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| | 0.1 | At traffic signals continue forward onto Saint Vincent's Avenue | Uncl. | 1.0 | |
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| | 0.3 | At traffic signals continue forward onto Headford Road | Uncl. | 1.3 | |
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| | 0.1 | At traffic signals continue forward onto Headford Road | Uncl. | 1.4 | |
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| | 0.5 | At Bodkin roundabout take the 2nd exit onto Headford Road - N6 | N6 | 1.9 | |
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| | 0.6 | At Kirwan roundabout take the 3rd exit onto Bothar Na Dtreabh - N6 (signposted Dublin) | N6 | 2.4 | |
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| | 1.9 | At Font roundabout take the 1st exit onto Tuam Road - N17 (signposted Sligo) | N17 | 4.4 | |
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| | 7.4 | Continue forward onto the N17 Entering Claregalway | N17 | 11.7 | |
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| | 0.1 | Continue forward onto the N17 (signposted Sligo) | N17 | 11.8 | |
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| | 20.9 | Continue forward onto the N17 Entering Tuam | N17 | 32.7 | |
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| | 14.8 | Continue forward onto the N17 Entering Milltown | N17 | 47.5 | |
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| | 7.5 | Continue forward onto the N17 Entering Ballindine | N17 | 55.1 | |
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| | 15.3 | (edge of) Knock | N17 | 70.3 | |
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| | 23.1 | Continue forward onto Ballyhaunis Road - N17 Entering Charlestown | N17 | 93.5 | |
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| | 0.4 | Turn left then right onto Market Square - N17 (signposted Sligo) | N17 | 93.9 | |
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| | 4.4 | Continue forward onto the N17 Entering Curry | N17 | 98.2 | |
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| | 6.6 | Continue forward onto the N17 Entering Tobercurry | N17 | 104.9 | |
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| | 16.0 | Continue forward onto the N17 Entering Ballynacarrow | N17 | 120.9 | |
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| | 7.5 | At roundabout take the 1st exit onto the N4 (signposted Sligo) | N4 | 128.3 | |
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| | 0.6 | At roundabout take the 2nd exit onto Dublin Road - N4 (signposted Sligo) | N4 | 129.0 | |
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| | 9.8 | Continue forward onto the N4 Entering Sligo | N4 | 138.8 | |
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| | 0.1 | At roundabout take the 1st exit onto Sligo Inner Relief Road - N4 (signposted Town Centre) | N4 | 138.9 | |
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| | 0.5 | At traffic signals continue forward onto Sligo Inner Relief Road - N4 | N4 | 139.4 | |
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| | 0.2 | At traffic signals continue forward onto Sligo Inner Relief Road - N4 | N4 | 139.6 | |
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| | 0.2 | At traffic signals continue forward onto Sligo Inner Relief Road - N4 | N4 | 139.9 | |
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| | 0.3 | At traffic signals continue forward onto Bundoran Road - N4 | N4 | 140.2 | |
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| | 0.3 | Turn right onto Duck Street - N16 (signposted Enniskillen) | N16 | 140.5 | |
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| | 0.2 | At roundabout take the 2nd exit onto Ash Lane - N16 | N16 | 140.7 | |
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| | 0.8 | At traffic signals turn left onto the N16 (signposted Enniskillen) | N16 | 141.5 | |
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| | 0.8 | At roundabout take the 1st exit onto Yeats Heights - N16 | N16 | 142.4 | |
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| | 23.4 | Bear right onto Sligo Road - N16 Entering Manorhamilton | N16 | 165.8 | |
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| | 1.0 | At roundabout take the 2nd exit onto Hillside Crescent - N16 | N16 | 166.8 | |
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| | 21.2 | Continue forward onto Main Street - N16 Entering Blacklion | N16 | 188.0 | |
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| | 0.6 | Continue forward onto Belcoo Road - N16 Entering Belcoo | N16 | 188.6 | |
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| | 0.1 | Continue forward onto Main Street - A4 (You are entering Northern Ireland) | A4 | 188.7 | |
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| | 13.8 | At Cappog Junction continue forward onto the A4 (signposted Sligo) | A4 | 202.6 | |
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| | 2.0 | At roundabout take the 1st exit onto Sligo Road - A4 (signposted Enniskillen) | A4 | 204.5 | |
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| | 1.5 | Continue forward onto Sligo Road - A4 Entering Enniskillen | A4 | 206.0 | |
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| | 2.1 | At roundabout take the 4th exit onto Dublin Road - A4 (signposted Dublin) | A4 | 208.1 | |
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| | 5.3 | Continue forward onto Tamlaght Road - A4 Entering Tamlaght | A4 | 213.4 | |
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| | 1.8 | At Leambreslen Junction continue forward onto the A4 (signposted Belfast) | A4 | 215.2 | |
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| | 5.1 | Tempo River | A4 | 220.3 | |
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| | 0.7 | Continue forward onto Belfast Road - A4 Entering Maguiresbridge | A4 | 221.0 | |
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| | 0.1 | Continue forward onto the A4 (signposted Belfast) | A4 | 221.1 | |
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| | 14.1 | Continue forward onto Colebrook Road - A4 Entering Fivemiletown | A4 | 235.2 | |
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| | 0.9 | Finish at Fivemiletown,Dungannon | A4 | 236.1 | |
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| | (End Section) | |
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